PNC-28

Synthetic p53-penetratin peptide analog for HDM-2 binding research and pancreatic cancer cell membrane interaction studies.

Product Description

PNC-28 is a synthetic 27-amino-acid chimeric peptide containing a shorter HDM-2 binding domain derived from p53 tumor suppressor protein (residues 17-26) fused to the same cell-penetrating peptide (CPP) sequence used in PNC-27. This membrane-active peptide represents a truncated analog that lacks the first five amino acids of PNC-27’s p53 domain while retaining selective cytotoxic activity against cancer cells.

Research investigations have examined PNC-28 in studies of HDM-2/p53 protein interactions, pancreatic cancer cell necrosis mechanisms, transmembrane pore formation, and penetratin-mediated cell entry pathways. The compound is used in controlled laboratory environments for investigating anticancer peptide structure-activity relationships, membrane disruption mechanisms, and selective tumor cell targeting in various cancer cell lines including pancreatic, ovarian, and breast cancer models. 

Supplied as pharmaceutical-grade lyophilized powder with third-party verified purity testing for qualified research institutions conducting in vitro research applications only.

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Every Limitless Biotech compound undergoes independent testing for endotoxins and sterility, meeting rigorous research standards through our systematic quality protocols and proactive manufacturing processes.

Buy PNC-28 Peptide From Limitless Biotech

Limitless Biotech provides USA-manufactured PNC-28 peptide for sale with verified molecular sequences and purity through comprehensive third-party testing. We ensure research quality with same-day shipping and dedicated customer support for your scientific endeavors.

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